Top 5 DTC Wellness Testing Options in the U.S. to Elevate Your Wellness Journey

17 Nov 2023

With increased awareness about wellness and fitness, people worldwide have started focusing on their physical and mental health conditions for prevention and early detection of health problems. 

After the disastrous impact of the COVID-19 pandemic, governments of nations around the world have started investing in advanced healthcare infrastructures, such as medical research facilities and digital health technologies, thereby preparing themselves for any future health crises and ensuring access to high-quality healthcare for their citizens. 

The direct-to-consumer (DTC) wellness testing options in the U.S. are becoming increasingly diverse and accessible, with many companies offering a wide range of at-home tests and services that allow individuals to take care of their health and wellness without having to visit a healthcare professional. 

The increasing availability of these DTC wellness testing options, such as genetic testing, blood tests, hormone tests, and food intolerance tests, provide insights into an individual’s health and wellness. 

1. DTC Hormone Testing

Hormones are vital in regulating various bodily functions, from managing stress levels to controlling metabolism. However, hormonal imbalances can cause a range of health issues, such as weight gain, mood swings, and fatigue. 

To handle these issues, people are turning to direct-to-consumer (DTC) hormone testing to understand better their hormonal health, which involves tests such as fertility testing, insulin sensitivity, and insulin resistance. Many companies are now offering test panels as a form of direct-to-consumer (DTC) testing, thereby allowing customers to test for multiple health markers at once. 

Some of the most common hormone-based tests include: 

  • Fertility Hormone Testing- A fertility test is carried out to monitor sperm count and measure hormone levels such as follicle-stimulating hormone (FSH),anti-Müllerian hormone (AMH), and estradiol levels. 
  • Insulin Sensitivity- Due to the increased incidence of diabetes in the U.S., insulin sensitivity varies from person to person, and physicians can perform tests to determine how sensitive an individual is to insulin. 
  • Insulin Resistance- Insulin resistance testing is essential as approximately 25% of the U.S. population has insulin resistance, which may lead to the development of type 2 diabetes and potential health threats such as strokes, heart attacks, and infertility in women. 
  • Thyroid Hormone Tests- This test measures the levels of thyroid hormones that play a crucial role in regulating metabolism, which includes thyroid-stimulating hormone (TSH), triiodothyronine (T3), and thyroxine (T4). 
  • Cortisol Tests- Cortisol tests check cortisol hormone levels, which help the body manage stress. 
  • Testosterone Tests- Testosterone levels are measured through these tests, a male reproductive hormone crucial in analyzing reproductive health and family planning. Higher testosterone levels in women lead to irregularity in menstruation and fertility. 
  • Progesterone Tests- These tests measure progesterone levels, a hormone essential for regulating the menstrual cycle and supporting pregnancy. 
For instance, Everlywell, a U.S.-based telehealth company, offers a $249 women’s health test, which measures eleven biomarkers in saliva and blood such as progesterone, estradiol, FSH, cortisol, TSH, T3, free testosterone, and dehydroepiandrosterone sulfate (DHEAS). 

DTC hormone testing involves collecting a blood or saliva sample and sending it to a laboratory for analysis, which provides a detailed report on the individual’s hormones and can help identify any imbalances that may be causing health issues. 

The results of the DTC testing can be used for medical interventions, such as lifestyle changes and supplement recommendations, to help balance hormone levels and improve overall health. 

The effectiveness and convenience of DTC testing and the demand for transparency in testing services are expected to drive the need for the U.S. direct-to-consumer wellness testing market in the near future. 

According to BIS Research, the U.S. DTC wellness testing market is projected to reach $4.94 billion by 2032 from $0.8 billion in 2022, at a CAGR of 18.86% during the forecast period 2022–2032.  

2. DTC Micronutrients Testing  

The increasing prevalence of nutrient deficiencies in the U.S. population due to unhealthy eating patterns is a primary reason, consumers are increasingly opting for micronutrient testing. 

DTC micronutrient testing measures the levels of various vitamins, minerals, and antioxidants in the body, which are required in significantly fewer quantities to ensure growth, normal metabolism, and physical well-being. DTC micronutrient testing involves intensive analysis of nutrient levels and deficiencies in the body for 40 minerals, antioxidants, vitamins, amino acids, fatty acids, and metabolites. 

3. DTC Food Intolerance Test 

Food intolerance is an adverse reaction to a particular food or food component that triggers a response from the immune system, which can also be life-threatening. 

Typical food intolerances include lactose intolerance, gluten intolerance, and sensitivity to certain food additives or chemicals, the diagnosis of which may lead to elimination diets and/or testing for specific food components or antibodies. 

A food sensitivity test measures the levels of immunoglobulin G (IgG) antibodies in response to certain foods, which is associated with delayed immune reactions. Increased IgG levels in response to a particular food may indicate an intolerance or sensitivity. 

The appearance of symptoms, such as migraine, irritable bowel, hives, headache, and joint pain, depends on an individual’s body and may vary from person to person. 

4. COVID-19 DTC Test

COVID-19 DTC tests allowed for convenient and accessible testing without needing to visit a healthcare provider during the COVID-19 pandemic as the world witnessed total lockdown.  

COVID-19 DTC testing involves a person collecting their sample, such as a nasal swab or saliva, and sending it to a laboratory for analysis. The test kits are typically purchased online or through a retail pharmacy, and the results are delivered directly to the individual. 

For instance, Everlywell, Inc. was the first to receive Emergency Use Authorization (EUA) for an at-home COVID-19 test kit that does not require a doctor’s prescription. Offer at-home COVID-19 test kits that can be used without eligibility screening. 

Other companies, like Innovative Health Diagnostics, offer at-home diagnostic tests, including the anti-mullerian hormone (AMH) and COVID-19 neutralizing antibody test (CNAB), which can detect SARS-CoV-2 neutralizing antibodies and provide insights into long-term immunity. 

5. Infectious Disease Tests

Infectious disease tests detect infectious agents, such as viruses, bacteria, fungi, or parasites, in a patient’s blood, bodily fluids, or tissue samples. These tests can help diagnose and monitor various infectious diseases, including sexually transmitted infections, hepatitis, tuberculosis, HIV/AIDS, and COVID-19. Different types of infectious disease tests exist, such as molecular, serological, and antigen tests. 

In recent times, there has been a shift toward direct-to-consumer healthcare services, allowing consumers to access medical and wellness benefits without having to visit a clinic or healthcare provider in person. In the wake of the COVID-19 pandemic, many hospitals and clinics have had to rely on online mechanisms to provide infectious disease testing remotely. 

This shift has increased demand for direct-to-consumer (DTC) infectious disease testing services through commercial entities, as consumers have become more comfortable with accessing healthcare services online. 


As the DTC wellness testing market grows, it is important to prioritize accuracy, reliability, and safety while selecting a testing provider. By leveraging the power of DTC wellness testing, individuals can take proactive steps toward achieving their health and wellness goals. 

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