Growth in Nucleic Acid Isolation and Purification Demand as its Application Areas Grow

04 Aug 2021

Nucleic acid isolation and purification is the preliminary step in the field of molecular biology research accompanied with recombinant techniques. The nucleic acid isolation process majorly includes enzymatic digestion and mechanical and chemical disruption.

The advantages offered by nucleic acid isolation and purification significantly aid scientists and researchers in obtaining high-quality material for conducting downstream applications and thereby generating accurate results.

The current impact of COVID-19 on the nucleic acid isolation and purification market has been considered positive. The current need for advanced and high-throughput solutions for sample testing has increased the demand for DNA/RNA isolation and purification kits globally.

In addition, the demand for nucleic acid-based diagnostics has also increased, which has led to several product launches and the development of automated bench-top instruments, sample collection devices, and rapid nucleic acid sample preparation solutions.

Recently, Central China's Zhengzhou launched citywide nucleic acid testing to understand the impact of COVID -19. In addition, several other cities of China have also implemented nucleic testing to understand the extent and impact of the COVID-19, as several cases have been detected.

According to the market intelligence report on Global Nucleic Acid Isolation and Purification Market published by BIS Research, the global nucleic acid isolation and purification market is expected to reach $5,010.3 million by 2031 from $2,304.7 million in 2020.

This growth is attributed to factors such as the rise in the field of microbial sequencing, increasing research funding in the field of molecular biology, increase in awareness and acceptance of personalized medicines on a global level, and decreasing cost of sequencing.

Nucleic acid isolation and purification enabled end users to conduct a wide variety of applications, and automation has further facilitated applications such as genomic/plasmid DNA, cell-free DNA (cfDNA), viral RNA, and cell-free RNA (cfRNA).

The advantages of genomic/plasmid DNA extraction include the involvement of simple and short procedures for minimizing the exposure time of DNA to other contaminants, followed by reducing degradation rates.

The isolation of cfDNA is majorly used in the field of non-invasive prenatal testing (NIPT) and precision oncology as cfDNA contains ctDNA, which is further utilized in the process of molecular analysis. Therefore, the isolation efficiency becomes critical for efficient ctDNA analysis utilizing downstream applications, particularly for disease detection.

In addition, automation in nucleic acid isolation and purification offers high throughput, further reducing sample processing time. Factors such as the increasing prevalence of genetic diseases, rising research in the field of molecular biology, growing awareness and acceptance of precision medicine worldwide, and rising research funding from government and private institutions, are further supporting the adoption of automated nucleic acid isolation and purification products.


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