Published Year: 2022
Cell-Free DNA Isolation and Extraction Market - A Global and Regional Analysis: Focus on Consumables
The global cell-free DNA isolation and extraction market was valued at $169.9 million in 2020...
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Industry and Technology Overview
Global Cell-Free Isolation and Extraction Kits Market
Industry Overview
The global cell-free RNA isolation and extraction kits market is projected to reach $140.7 million by 2032 from $30.2 million in 2021, growing at a CAGR of 14.98% during the forecast period 2022-2032. The growth in the cell-free RNA isolation and extraction kits market is expected to be driven by an increasing number of kits and a rising number of open-source free sequencing platform providers offering cell-free RNA analysis.
Market Lifecycle Stage
The cell-free RNA isolation and extraction kits market is a well-developed market with an integral part of medical decision-making -aid in acquiring information for a wide range of treatment dissemination, accentuating their criticality in healthcare. The cell-free RNA has a critical role in the precision medicine approach, as it ensures the safe and effective application of targeted therapeutics. Most of the players in the global cell-free RNA isolation and extraction kits market offer products encompassing the kits.
Increasing investments in the R&D for cell-free RNA isolation and extraction is one of the major opportunities in the global cell-free RNA isolation and extraction kits market. Several biotechnology and pharmaceutical companies are working collaboratively to adopt cell-free RNA isolation and extraction in the field of oncology, prenatal screening, and metabolic disorders.
Figure: Global Cell-Free RNA Isolation and Extraction Kits Market Snapshot
Source: BIS Research Analysis
Impact
• The presence of major products of cell-free RNA isolation and extraction kits in regions such as North America and APAC has a major impact on the market. For instance, QIAGEN N.V. provides cell-free RNA isolation and extraction kits.
• Companies such as Zinexts Life Science Corp. and JBS Science, Inc. enter into a technology commercialization cooperation agreement to allow Zinexts to manufacture and sell JBS nucleic separation kits, including cfDNA and RNA isolation kits. This license agreement will make it easier to access JBS NA Zinexts's JBS NA isolation equipment as well as their isolation automation systems The presence of these companies has a positive impact on the market growth.
Impact of COVID-19
The current global cell-free RNA isolation and extraction kits market study comprises cell-free RNA isolation and extraction kits that are used to extract and isolate cell-free RNA form samples collected from patients and preserve cell-free RNA for further downstream analysis to retrieve actionable information from it. Since the market is primarily dominated by the manufacturers of cell-free RNA isolation and extraction kits, the pandemic had a negative impact on the growth of revenue generated from the market. Players in the cell-free RNA isolation and extraction kits market reported a decline in revenues during the initial phase of the pandemic. The decline was primarily attributed to the lockdown in the regions that disrupted the supply chain, thereby hampering the cancer diagnostic testing. Additionally, a halt in research and development activities pertaining to cell-free RNA for oncology, prenatal screening, and metabolic disorders market also led to a decline in revenue. Moreover, in order to curb the spread of the SARS-CoV-2 virus, and contain the spread of the virus, demand for COVID-19 tests and services that detects the virus in less time increased, which led to the shift in focus of the manufacturers for developing and manufacturing testing kits and services for the detection of SARS-CoV-2 virus.
Market Segmentation:
Segmentation 1: by Application
• Oncology
• Prenatal Screening (Preeclampsia)
• Metabolic Disorders
The oncology segment accounted for the largest share of 79.85% in the global cell-free RNA isolation and extraction kits market in 2021.
Segmentation 2: by End User
• Hospitals
• Academic Research Institutions and Laboratories
• Pharmaceutical and Biotechnology Companies
• Diagnostic Laboratories
The academic research institutions and laboratories segment accounted for the largest share of 63.13% in the global cell-free RNA isolation and extraction kits market in FY2021.
Segmentation 3: by Region
• North America
• Europe
• Asia-Pacific
• Latin America
• Rest-of-the-World
North America cell-free RNA isolation and extraction market dominated the global cell-free RNA isolation and extraction kits market and is expected to maintain its dominance over other regions throughout the forecast period 2022-2032.
Recent Developments in Global Cell-Free RNA Isolation and Extraction Kits Market
• In February 2022, Zinexts Life Science Corp. and JBS Science, Inc. enter into a technology commercialization cooperation agreement to allow Zinexts to manufacture and sell JBS nucleic separation kits, including cfDNA and RNA isolation kits. This license agreement will make it easier to access JBS NA Zinexts's JBS NA isolation equipment as well as their isolation automation systems.
• In February 2019, Norgen Biotek Corp. introduced the cf-DNA / cf-RNA Preservative Tubes for long-term storage of blood. These are more suitable blood collection tubes (BCTs) as compared to other competitor’s blood collection tubes (BCTs) in the cell-free RNA market. This is the only product that keeps both cf-DNA and cf-RNA in the same tube for 30 days, allowing researchers to examine both genomics and transcriptomics.
Demand – Drivers and Limitations
Following are the demand drivers for the Global Cell-Free RNA Isolation and Extraction Kits Market:
• Increasing Incidence of Cancer
• Increasing Number of Cases with Prenatal Complications
• Advancement in the RNA Sequencing Technology
The market is expected to face some limitations too due to the following challenges:
• Lack of Skilled Professionals and Awareness Related to Cell-Free RNA Methods
• Ethical, Legal, and Social Issues Associated with Prenatal Screening
Analyst Thoughts
According to Nitish Kumar, Principal Analyst, BIS Research, “Global Cell-Free RNA Isolation and Extraction Kits Market has gained momentum recently. With increase in research activities and funding to promote the utilization of cell-free RNA for early detection of a disease condition and decipher insights to provide personalized treatment to patients would enable the market to propel during the forecast period 2022-2032."
Cell-Free RNA Isolation and Extraction Kits Market - A Global and Regional Analysis
Focus on Application, End User, and Region - Analysis and Forecast, 2022-2032
Some Faq's
Frequently Asked Questions
Cell-free RNA (cfRNA) naturally occurs in cell free fluids and represents an opportunity to detect tumor in patients with lower tumor shedding rates. CfRNA is involved in cell communications and has been linked to physical and pathological conditions. As a result, cfRNA has been proposed as a potential biomarker for cancer related mutations, prenatal screening, and metabolic disorders
The key trends in the global cell-free RNA isolation and extraction kits market include cell-free RNA isolation and extraction products that have witnessed significant growth due to several launches. For instance, In March 2020, JBS Science, Inc., has introduced the semi-automated JPurX-S200 cell-free nucleic acid purification system. The system employs magnetic bead coating particles to purify cfRNA/cfDNA from body fluids. With the launch of new product, the company has expanded its range cell free nucleic acid purification kits.
The global cell-free RNA isolation and extraction market has seen major development by key players operating in the market, such as business expansion, partnership, collaboration, and joint venture. According to BIS Research analysis, the majority of the companies preferred partnerships, collaborations, and joint ventures as a strategy to further increase their growth in the global cell-free RNA isolation and extraction market. Companies such as Thermo Fisher Scientific Inc., F-Hoffmann-La Roche Ltd., QIAGEN N.V, have majorly adopted partnerships, collaborations, and joint venture strategies.
A new entrant can focus on various new technologies being used for diagnosis and services that are being offered by the established market players of the cell-free RNA.
• Extensive competitive benchmarking of the top 13 players has been done to offer a holistic view of the global cell-free RNA isolation and extraction kits market landscape
• Market ranking analysis based on product portfolio, recent developments, and regional spread
• Investment landscape including product adoption scenario, funding, and patent analysis
The cell-free RNA isolation and extraction kit service providers, technology providers, pharmaceutical companies, and research institutions, should buy this report.
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