A quick peek into the report
Table of Contents
1.1 Market Overview and Ecosystem
1.2 Epidemiological Analysis
1.3 Key Market Trends
1.3.1 Impact Analysis
1.4 Regulatory Landscape
1.5 Pipeline Analysis
1.6 Market Dynamics
1.6.1 Overview
1.6.2 Market Drivers
1.6.3 Market Restraints
1.6.4 Market Opportunities
2.1 North America
2.1.1 Market Dynamics
2.1.2 Market Sizing and Forecast
2.1.3 North America Liver Fibrosis Market, by Country ($Million), 2023-2035
2.1.3.1 U.S.
2.2 Europe
2.2.1 Market Dynamics
2.2.2 Market Sizing and Forecast
2.2.3 Europe Liver Fibrosis Market, by Country ($Million), 2023-2035
2.2.3.1 U.K.
2.2.3.2 France
2.2.3.3 Germany
2.2.3.4 Italy
2.2.3.5 Spain
2.3 Asia-Pacific
2.3.1 Market Dynamics
2.3.2 Market Sizing and Forecast
2.3.3 Asia-Pacific Liver Fibrosis Market, by Country ($Million), 2023-2035
2.3.3.1 Japan
3.1 Competitive Landscape
3.1.1 Mergers and Acquisitions
3.1.2 Partnership, Alliances and Business Expansion
3.1.3 New Offerings
3.1.4 Regulatory Activities
3.1.5 Funding Activities
3.2 Company Profiles
3.2.1 Akero Therapeutics.
3.2.1.1 Overview
3.2.1.2 Top Products / Product Portfolio
3.2.1.3 Top Competitors
3.2.1.4 Target Customers/End-Users
3.2.1.5 Key Personnel
3.2.1.6 Analyst View
3.2.2 Sagimet Biosciences.
3.2.2.1 Overview
3.2.2.2 Top Products / Product Portfolio
3.2.2.3 Top Competitors
3.2.2.4 Target Customers/End-Users
3.2.2.5 Key Personnel
3.2.2.6 Analyst View
3.2.3 Boehringer Ingelheim.
3.2.3.1 Overview
3.2.3.2 Top Products / Product Portfolio
3.2.3.3 Top Competitors
3.2.3.4 Target Customers/End-Users
3.2.3.5 Key Personnel
3.2.3.6 Analyst View
3.2.4 89bio.
3.2.4.1 Overview
3.2.4.2 Top Products / Product Portfolio
3.2.4.3 Top Competitors
3.2.4.4 Target Customers/End-Users
3.2.4.5 Key Personnel
3.2.4.6 Analyst View
3.2.5 Inventiva Pharma.
3.2.5.1 Overview
3.2.5.2 Top Products / Product Portfolio
3.2.5.3 Top Competitors
3.2.5.4 Target Customers/End-Users
3.2.5.5 Key Personnel
3.2.5.6 Analyst View
3.2.6 Galmed Pharmaceuticals.
3.2.6.1 Overview
3.2.6.2 Top Products / Product Portfolio
3.2.6.3 Top Competitors
3.2.6.4 Target Customers/End-Users
3.2.6.5 Key Personnel
3.2.6.6 Analyst View
3.2.7 Novo Nordisk A/S.
3.2.7.1 Overview
3.2.7.2 Top Products / Product Portfolio
3.2.7.3 Top Competitors
3.2.7.4 Target Customers/End-Users
3.2.7.5 Key Personnel
3.2.7.6 Analyst View
3.2.8 Viking Therapeutics.
3.2.8.1 Overview
3.2.8.2 Top Products / Product Portfolio
3.2.8.3 Top Competitors
3.2.8.4 Target Customers/End-Users
3.2.8.5 Key Personnel
3.2.8.6 Analyst View
3.2.9 Hepion Pharmaceuticals.
3.2.9.1 Overview
3.2.9.2 Top Products / Product Portfolio
3.2.9.3 Top Competitors
3.2.9.4 Target Customers/End-Users
3.2.9.5 Key Personnel
3.2.9.6 Analyst View
3.2.10 Pfizer, Inc.
3.2.10.1 Overview
3.2.10.2 Top Products / Product Portfolio
3.2.10.3 Top Competitors
3.2.10.4 Target Customers/End-Users
3.2.10.5 Key Personnel
3.2.10.6 Analyst View
3.2.11 HighTide Biopharma.
3.2.11.1 Overview
3.2.11.2 Top Products / Product Portfolio
3.2.11.3 Top Competitors
3.2.11.4 Target Customers/End-Users
3.2.11.5 Key Personnel
3.2.11.6 Analyst View
3.2.12 Boston Pharmaceuticals.
3.2.12.1 Overview
3.2.12.2 Top Products / Product Portfolio
3.2.12.3 Top Competitors
3.2.12.4 Target Customers/End-Users
3.2.12.5 Key Personnel
3.2.12.6 Analyst View
3.2.13 Rivus Pharmaceuticals.
3.2.13.1 Overview
3.2.13.2 Top Products / Product Portfolio
3.2.13.3 Top Competitors
3.2.13.4 Target Customers/End-Users
3.2.13.5 Key Personnel
3.2.13.6 Analyst View
3.2.14 Lipocine.
3.2.14.1 Overview
3.2.14.2 Top Products / Product Portfolio
3.2.14.3 Top Competitors
3.2.14.4 Target Customers/End-Users
3.2.14.5 Key Personnel
3.2.14.6 Analyst View
3.2.15 Aligos Therapeutics.
3.2.15.1 Overview
3.2.15.2 Top Products / Product Portfolio
3.2.15.3 Top Competitors
3.2.15.4 Target Customers/End-Users
3.2.15.5 Key Personnel
3.2.15.6 Analyst View
3.2.16 MediciNova.
3.2.16.1 Overview
3.2.16.2 Top Products / Product Portfolio
3.2.16.3 Top Competitors
3.2.16.4 Target Customers/End-Users
3.2.16.5 Key Personnel
3.2.16.6 Analyst View
3.2.17 Eli Lilly and Company.
3.2.17.1 Overview
3.2.17.2 Top Products / Product Portfolio
3.2.17.3 Top Competitors
3.2.17.4 Target Customers/End-Users
3.2.17.5 Key Personnel
3.2.17.6 Analyst View
3.2.18 Others
Table: Global Liver Fibrosis Market Dynamics, Impact Analysis
Table: Global Liver Fibrosis Market (by Region), $Million, 2023-2035
Figure: Global Liver Fibrosis Market Coverage
Figure: Global Liver Fibrosis Market Key Trends, Impact Analysis, 2023-2035
Liver Fibrosis Market Report Coverage
|
Global Liver Fibrosis Market |
|||
|
Market Size in 2023 |
$1.8 Billion |
Value Projection and Estimation by 2035 |
$ XX Billion |
|
Forecast Period |
2025-2035 |
Approx. CAGR During Forecast Period |
XX% |
Key Questions Answered
• What are the main factors driving the demand for the liver fibrosis market?
• What is the epidemiology of liver fibrosis?
• What are the status of clinical trails in the liver fibrosis market?
• Who are the key players in the liver fibrosis market, and what are their respective market shares?
• What partnerships or collaborations are prominent among stakeholders in the liver fibrosis market?
• What are the strategies adopted by the key companies to gain a competitive edge in the liver fibrosis market?
• What is the futuristic outlook for the liver fibrosis market in terms of growth potential?
• What is the current estimation of the liver fibrosis market, and what growth trajectory is projected from 2025 to 2035?
• Which regions demonstrate the highest adoption rates for the liver fibrosis market, and what factors contribute to their leadership?
Global Liver Fibrosis Market, Analysis and Forecast: 2025-2035
Liver fibrosis is a progressive liver disease characterized by the accumulation of scar tissue in the liver, resulting from chronic liver damage due to various underlying conditions such as hepatitis, alcohol use, obesity, or autoimmune diseases. As the liver attempts to heal itself from injury, excessive collagen and other extracellular matrix components are produced, leading to fibrosis. If left untreated, liver fibrosis can progress to cirrhosis, chronic liver failure, or even liver cancer. The severity of liver fibrosis is often classified into stages, with early stages being reversible but more advanced stages leading to permanent damage.
While liver fibrosis is currently a significant health concern, advancements in diagnostic technologies and treatments are helping to manage the disease more effectively. Antifibrotic therapies, such as antivirals for hepatitis-related fibrosis and medications that target fibrosis pathways, are emerging as key treatment options. Liver transplantation remains the only definitive cure for end-stage liver fibrosis or cirrhosis, though it is limited by donor availability.
The prevalence of various liver diseases, including autoimmune hepatitis, non-alcoholic fatty liver disease (NAFLD), alcoholic liver disease, chronic hepatitis B and C, and liver fibrosis, is steadily increasing. As these conditions progress, they often lead to liver fibrosis, which is becoming more common globally. The growing incidence of liver fibrosis is expected to drive the market for its treatment. Key risk factors such as chronic hepatitis B or C, co-infection with HIV/AIDS, and the use of immunosuppressive drugs following liver transplantation are contributing to the rising demand for liver fibrosis treatments. According to a study by the National Center for Biotechnology Information, liver disease is projected to become a major global health issue in 2023, contributing to an estimated 4% of global mortality. Thus, the worldwide surge in liver fibrosis cases is further propelling market growth.
Additionally, the growing understanding of the molecular mechanisms involved in liver fibrosis is fuelling the development of targeted therapies. Research into specific fibrosis pathways, such as TGF-β signaling and the role of immune cells in fibrosis progression, has led to the discovery of promising therapeutic agents. Non-invasive diagnostic tools, such as liver elastography and blood biomarkers, are also making it easier to detect liver fibrosis early, enabling more timely intervention and better management of the disease.
Despite these advances, the liver fibrosis market faces several challenges. One significant hurdle is the lack of approved, effective antifibrotic therapies. While several drug candidates are in clinical trials, there are few approved therapies available to treat liver fibrosis, especially for advanced stages. This has led to a gap in treatment options for patients with severe fibrosis or cirrhosis. Moreover, the complexity of the disease and its progression, along with the difficulty of accurately staging liver fibrosis without invasive procedures, complicates both diagnosis and treatment.
Another challenge is the high cost of treatment, particularly for advanced therapies such as liver transplantation and novel biologics targeting fibrosis. These treatments often come with high costs, placing financial strain on healthcare systems and patients, especially in developing regions where access to care may be limited.
The global liver fibrosis market is highly competitive, with several leading companies driving innovation and market growth, such as Akero Therapeutics, Sagimet Biosciences, Inventiva Pharma, Novo Nordisk, Viking Therapeutics, Boston Pharmaceuticals, Aligos Therapeutics, Boehringer Ingelheim, and 89bio. These companies are at the forefront of developing novel therapies that are significantly improving patient outcomes. Through strategic investments in research and development (R&D), expanding product portfolios, and increasing global access to cutting-edge treatments, these industry leaders are shaping the future of liver fibrosis care and contributing to the dynamic growth of the market. Additionally, expanding into emerging markets and increasing their presence through regional distribution networks are key strategies to tap into underserved patient populations. These strategies are enabling companies to strengthen their market position and accelerate growth in the competitive liver fibrosis treatment landscape.
Liver Fibrosis Market Segmentation:
Segmentation 1: by Region
• North America
• Europe
• Asia-Pacific
The global liver fibrosis market is undergoing significant transformation, fueled by emerging trends that are reshaping treatment paradigms and driving liver fibrosis market growth. The integration of artificial intelligence (AI) into liver fibrosis treatment holds immense potential to revolutionize both diagnosis and treatment. AI can significantly enhance the ability to diagnose liver fibrosis early and accurately by analyzing vast amounts of patient data, including imaging, biomarkers, and genetic information. Machine learning algorithms are already being developed to interpret non-invasive tests like elastography and CT scans, offering faster and more reliable assessments of liver damage, which can improve the speed of diagnosis and allow for earlier intervention.
The expansion of the liver fibrosis market into emerging regions presents a significant growth opportunity due to several factors. As healthcare infrastructure improves in regions such as Asia-Pacific, Latin America, and parts of Africa, the demand for liver fibrosis treatments is expected to rise. These regions are witnessing an increasing prevalence of liver diseases, particularly as risk factors such as obesity, alcohol consumption, and hepatitis become more widespread. Furthermore, the aging population in these regions is leading to a higher incidence of chronic liver diseases and fibrosis.
Liver Fibrosis Market - A Global and Regional Analysis
Focus on Country and Region - Analysis and Forecast, 2025-2035
Frequently Asked Questions
Ans: The global liver fibrosis market was valued at approximately USD XX billion in 2023 and is projected to reach USD XX billion by 2035, exhibiting a compound annual growth rate (CAGR) of approx. XX% from 2025 to 2035.
Ans: Major players in the global liver fibrosis market include Akero Therapeutics, Sagimet Biosciences, Inventiva Pharma, Novo Nordisk, Viking Therapeutics, Boston Pharmaceuticals, Aligos Therapeutics, Boehringer Ingelheim, and 89bio, among others.
Trends:
• Increasing government initiatives and support
• Increasing development of combination therapies
Driver:
• Increasing research and development activities by key players
• Increasing prevalence of liver fibrosis
• Lack of approved, effective antifibrotic therapies
• High cost of treatment and drug development
• Expansion of the liver fibrosis market into emerging regions
• Integration of artificial intelligence in the liver fibrosis treatment