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Our healthcare experts have found viral vector and plasmid manufacturing industry to be one of the most rapidly evolving market, and the global market for viral vector and plasmid manufacturing is predicted to grow at a CAGR of 16.28% over the forecast period of 2020-2030.
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Market Report Coverage - Viral Vector and Plasmid Manufacturing Market |
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Base Year |
2019 |
Market Size in 2019 |
$1,158.44 Million |
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Forecast Period |
2020-2030 |
Value Projection and Estimation by 2030 |
$ 5,862.22 Million |
|
CAGR During Forecast Period |
16.28% |
Number of Tables |
14 |
|
Number of Pages |
275 |
Number of Figures |
157 |
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Research Hours |
700 |
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Market Segmentation |
• Vector Type – Plasmid DNA and Viral Vector • Viral Vector Type – Adenovirus, Adeno-Associated Virus, Retrovirus, Lentivirus, Vaccinia Virus, and Other Viral Vectors • Disease Type – Cancer, Genetic Disease, Infectious Disease, Cardiovascular Disease, and Other Diseases • Application – Gene Therapy, Cell Therapy, Vaccinology, and Other Applications |
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Regional Segmentation |
• North America – U.S., Canada • Europe – Germany, U.K., France, Italy, Switzerland, Belgium Spain, and Rest-of-Europe • Asia-Pacific – China, Australia, Japan, India, South Korea, Singapore, and Rest-of-Asia-Pacific • Rest-of-the-World – Latin America and Middle-East and Africa |
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Growth Drivers |
• Rising Prevalence of Cancer, Genetic Disorders, and Infectious Diseases • Rapid Uptake of Viral and Plasmid Vectors for the Development of Innovative Therapies • Increasing Number of Clinical Studies for the Development of Gene Therapy • Favorable Funding Scenario for Vector-Based Therapies |
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Market Challenges |
• Unaffordable Cost of Gene Therapies • High Manufacturing Costs of Viral Vectors and Plasmids • Complications Associated with Large-Scale Production of Vectors |
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Market Opportunities |
• Rising Demand for Synthetic Genes • Emergence of Next-Generation Vectors
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Key Companies Profiled |
FUJIFILM Holdings Corporation, GENERAL ELECTRIC, Lonza, Merck KGaA, MolMed S.p.A., Novasep Holding, Oxford Biomedica plc, Catalent, Inc., Thermo Fisher Scientific, Inc., GenScript, Boehringer Ingelheim, Wuxi AppTec Co., Ltd., Sartorius AG, Takara Bio Inc., and Aldevron, L.L.C. |
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Key Questions Answered:
• What is a vector and what is its importance in the medical industry? What are the major characteristics and types of vectors? What are the areas of application of vectors?
• What are the major advancements in viral vector and plasmid manufacturing? What are the key trends of the global viral vector and plasmid manufacturing market? How is the market evolving and what is its future scope?
• What are the major drivers, challenges, and opportunities of the global viral vector and plasmid manufacturing market?
• What are the key developmental strategies implemented by the key players of the global viral vector and plasmid manufacturing market to sustain the competition of the market? What is the percentage share of each of the key players in different key developmental strategies?
• What is the regulatory scenario of the global viral vector and plasmid manufacturing market? What are the initiatives implemented by different governmental bodies and guidelines put forward to regulate the commercialization of viral vector and plasmid manufacturing products?
• What are major milestones in patenting activity in the global viral vector and plasmid manufacturing market?
• What was the market size of the global viral vector and plasmid manufacturing market in 2019 and what is the market size anticipated to be in 2030? What is the expected growth rate of the global viral vector and plasmid manufacturing market during the period between 2020 and 2030?
• What is the global market size for manufacturing plasmids and different types of viral vectors available in the global viral vector and plasmid manufacturing market in 2019? What are the key trends of the market with respect to different vectors and which vector type is expected to dominate the market in 2030?
• What are the different disease areas where plasmids and viral vectors are employed in the global viral vector and plasmid manufacturing market? Which disease type dominated the market in 2019 and is expected to dominate in 2030?
• What are the different applications associated with viral vector and plasmid manufacturing? What was the contribution of each of the application areas in the global viral vector and plasmid manufacturing market in 2019 and what is it expected in 2030?
• Which region is expected to contribute the highest sales in the global viral vector and plasmid manufacturing market during the period between 2019 and 2030? Which region and country carries the potential for the significant expansion of key companies for different viral vector and plasmid manufacturing? What are the leading countries of different regions that contribute significantly toward the growth of the viral vector and plasmid manufacturing market?
• What are the key players of the global viral vector and plasmid manufacturing market and what is their role in the market? What is the market share of the key players in 2019?
Market Overview
The ability of vectors to carry out genetic modification through the introduction of therapeutic DNA/gene into a patient's body or cell has enabled its application in a wide range of modern therapies, including cell and gene therapies. Growing prominence of these therapies in different medical applications have therefore resulted in an increased demand for both viral and non-viral vectors. Vector-based therapies are currently being used for the treatment of a large number of diseases, including cancer, infectious diseases, genetic diseases, and cardiovascular diseases, among others. Viral vectors and plasmid reduce the cost of treatment and help in decreasing repeated administrations of medications. Moreover, vectors are also increasingly being used in the field of vaccinology for the development of vaccines owing to the advantage offered by them in inducing a wide range of immune response types. Several players, including biopharmaceutical companies, research institutes, contract manufacturing organizations, and non-profit organizations, have therefore focussed their interest on the development and production of viral vectors and plasmids.
Our healthcare experts have found viral vector and plasmid manufacturing industry to be one of the most rapidly evolving market, and the global market for viral vector and plasmid manufacturing is predicted to grow at a CAGR of 16.28% over the forecast period of 2020-2030. The market is driven by certain factors, which include success of vector-based cell and gene therapies in treating various therapeutic conditions, increasing number of clinical studies in the field of gene therapy and availability of funding for vector-based gene therapy development, technological advancements in the biomanufacturing sector, and growing investments for expanding vector manufacturing facilities.
The market is favoured by the rising prevalence of genetic disorders, cancer, and infectious diseases that has raised the demand for advanced therapeutics and increasing acceptance for comparatively newer treatment options in developing countries. However, the growth of the market is also affected by several factors. Exorbitant manufacturing cost and highly regulated processes for large-scale vector production are the key challenges cited by industry experts. In addition, lack of required infrastructure and the shortfall of expertise in terms of scale, complexities, and quality assurance for vector production are some of the factors restraining the market growth. However, rise of contract manufacturers has effectively addressed the above-articulated manufacturing challenges by offering a wide range of vector manufacturing services that offer lucrative opportunities for the growth of the market. Further, increasing in research and developmental activities in vector engineering offer strong promise to drive the growth of the viral vector and plasmid manufacturing market in the upcoming years.
Within the research report, the market is segmented on the basis of vector type, application, disease, and region. Each of these segments covers the snapshot of the market over the projected years, the inclination of the market revenue, underlying patterns, and trends by using analytics on the primary and secondary data obtained.
Competitive Landscape
The exponential rise in the application of viral vector and plasmid in various therapies on the global level has created a buzz among companies to invest significantly in viral vector and plasmid manufacturing market. The market is highly competitive, marking the presence of several contract manufacturing organizations and biopharmaceutical companies, who are engaged in in-house vector manufacturing. Among the different players of the market, Lonza and Thermo Fisher Scientific hold majority of the market share. Other companies contributing significantly toward the growth of the global viral vector and plasmid manufacturing market include GE Healthcare, Fujifilm Holding Corporation, Merck KGaA, Oxford Biomedica plc, Sartorius AG, and Catalent, Inc., among others. On the basis of region, North America holds the largest market share, while Asia-Pacific region are anticipated to grow at the fastest CAGR during the forecast period.
List of Tables
Table 1: Leading Segments of the Global Viral Vector and Plasmid Manufacturing Market, 2019 and 2030
Table 4.1: Advantages and Disadvantages of Common Viral Vectors and Plasmids
Table 5.1: Gene Therapy for Different Types of Cancer
Table 5.2: Recent Approvals for Gene Therapy
Table 5.3: Companies Offering Gene Therapies and Their Cost
Table 6.1: Global Regulatory Scenario
Table 6.2: Patents Related to Viral Vectors and Plasmids (January 2017-February 2020)
Table 8.1: Examples of Viral Vectors Used in Gene Therapy
Table 8.2: Plasmids Used in Gene Therapy Trials
Table 9.1: Examples of Ad Vectors for Cancer Gene Therapy
Table 9.2: Features of Vectors Used in Cardiovascular Therapy
Table 10.1: Examples of Clinical Trials Using Viral Vectors
Table 10.2: Advantages and Disadvantages Associated with Major Viral Vectors
Table 11.1: Examples of Key Companies with Headquarters in the U.S.
List of Figures
Figure 1: Global Viral Vector and Plasmid Manufacturing Market (by Region), 2019 and 2030
Figure 2: Key Players of the Global Viral Vector and Plasmid Manufacturing Market
Figure 3: Drivers, Challenges, and Opportunities of the Global Viral Vector and Plasmid Manufacturing Market
Figure 4: Share of Key Developments and Strategies, January 2017-February 2020
Figure 5: Global Viral Vector and Plasmid Manufacturing Market (by Vector Type), 2019 and 2030
Figure 6: Global Viral Vector and Plasmid Manufacturing Market (by Viral Vector), 2019 and 2030
Figure 7: Global Viral Vector and Plasmid Manufacturing Market (by Disease), 2019 and 2030
Figure 8: Global Viral Vector and Plasmid Manufacturing Market (by Application), 2019 and 2030
Figure 2.1: Global Viral Vector and Plasmid Manufacturing Market Segmentation
Figure 3.1: Global Viral Vector and Plasmid Manufacturing Market Research Methodology
Figure 3.2: Primary Research
Figure 3.3: Secondary Research
Figure 3.4: Data Triangulation
Figure 3.5: Bottom-up Approach (Segment-Wise Analysis)
Figure 3.6: Top-Down Approach (Segment-Wise Analysis)
Figure 3.7: Assumptions and Limitations
Figure 4.1: Mechanism of Action of Vectors
Figure 4.2: Evolutionary History of Vectors
Figure 4.3: Typical Production Methods of Viral Vectors and Plasmids
Figure 4.4: Global Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 5.1: Drivers, Challenges, and Opportunities of the Global Viral Vector and Plasmid Manufacturing Market
Figure 5.2: Estimated New Cancer Cases and Deaths (by Sex), U.S., 2020
Figure 6.1: Workflow Associated With Biomanufacturing
Figure 6.2: Global Viral Vector and Plasmid Manufacturing Market: Patent Analysis (by Year of Publication), June 2017-December 2019
Figure 7.1: Competitive Landscape, January 2017- March 2020
Figure 7.2: Share of Key Developments and Strategies, January 2017-February 2020
Figure 7.3: Partnerships and Alliances (by Company), January 2017-February 2020
Figure 7.4: Business Expansions (by Company), January 2017-February 2020
Figure 7.5: New Offerings (by Company), January 2017-February 2020
Figure 7.6: M&A Activities (by Company), January 2017-February 2020
Figure 7.7: Others (by Company), January 2017-February 2020
Figure 7.8: Market Share Analysis of Global Viral Vector and Plasmid Manufacturing Market, 2019
Figure 8.1: Global Viral Vector and Plasmid Manufacturing Market Segmentation (by Vector)
Figure 8.2: Global Viral Vector and Plasmid Manufacturing Market (by Vector Type), 2019 and 2030
Figure 8.3: Global Viral Vector and Plasmid Manufacturing Market for Viral Vectors, 2019-2030
Figure 8.4: Global Viral Vector and Plasmid Manufacturing Market (by Viral Vector), 2019 and 2030
Figure 8.5: Global Viral Vector and Plasmid Manufacturing Market for Adenoviral Vectors, 2019-2030
Figure 8.6: Global Viral Vector and Plasmid Manufacturing Market for Retroviral Vectors, 2019-2030
Figure 8.7: Global Viral Vector and Plasmid Manufacturing Market for Adeno-Associated Viral Vectors, 2019-2030
Figure 8.8: Global Viral Vector and Plasmid Manufacturing Market for Lentiviral Vectors, 2019-2030
Figure 8.9: Global Viral Vector and Plasmid Manufacturing Market for Vaccinia Viral Vectors, 2019-2030
Figure 8.10: Global Viral Vector and Plasmid Manufacturing Market for Other Viral Vectors, 2019-2030
Figure 8.11: Global Viral Vector and Plasmid Manufacturing Market for Viral Vectors, 2019-2030
Figure 9.1: Global Viral Vector and Plasmid Manufacturing Market Segmentation (by Disease)
Figure 9.2: Global Viral Vector and Plasmid Manufacturing Market (by Disease), 2019 and 2030
Figure 9.3: Global Viral Vector and Plasmid Manufacturing Market for Cancer, 2019-2030
Figure 9.4: List of Monogenic Disorders for which Human Gene Transfer Trials Have Been Approved
Figure 9.5: Global Viral Vector and Plasmid Manufacturing Market for Genetic Diseases, 2019-2030
Figure 9.6: Global Viral Vector and Plasmid Manufacturing Market for Infectious Diseases, 2019-2030
Figure 9.7: Global Viral Vector and Plasmid Manufacturing Market for Infectious Diseases, 2019-2030
Figure 9.8: Global Viral Vector and Plasmid Manufacturing Market for Other Diseases, 2019-2030
Figure 10.1: Global Viral Vector and Plasmid Manufacturing Market Segmentation (by Application)
Figure 10.2: Global Viral Vector and Plasmid Manufacturing Market (by Application), 2019 and 2030
Figure 10.3: Global Viral Vector and Plasmid Manufacturing Market for Gene Therapy, 2019-2030
Figure 10.4: Global Viral Vector and Plasmid Manufacturing Market for Vaccinology, 2019-2030
Figure 10.5: Global Viral Vector and Plasmid Manufacturing Market for Cell Therapy, 2019-2030
Figure 10.6: Global Viral Vector and Plasmid Manufacturing Market for Cell Therapy, 2019-2030
Figure 11.1: Global Viral Vector and Plasmid Manufacturing Market (by Region), 2019 and 2030
Figure 11.2: North America: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.3: North America: Market Dynamics
Figure 11.4: North America: Viral Vector and Plasmid Manufacturing Market (by Country), 2019 and 2030
Figure 11.5: U.S.: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.6: Canada: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.7: Europe: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.8: Europe: Market Dynamics
Figure 11.9: Europe: Viral Vector and Plasmid Manufacturing Market (by Country), 2019 and 2030
Figure 11.10: Germany: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.11: U.K.: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.12: France: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.13: Italy: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.14: Switzerland: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.15: Belgium: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.16: Spain: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.17: Rest-of-Europe: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.18: Asia-Pacific: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.19: Asia-Pacific: Market Dynamics
Figure 11.20: Asia-Pacific: Viral Vector and Plasmid Manufacturing Market (by Country), 2019 and 2030
Figure 11.21: China: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.22: Australia: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.23: Japan: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.24: India: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.25: South Korea: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.26: Singapore: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.27: Rest-of-Asia-Pacific: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.28: Rest-of-the-World: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.29: Rest-of-the-World: Viral Vector and Plasmid Manufacturing Market (Latin America and Middle-East and Africa), 2019-2030
Figure 12.1: Shares of Key Company Profiles
Figure 12.2: Aldevron, LLC: Service / Product Portfolio for Global Viral Vector and Plasmid Manufacturing Market
Figure 12.3: Aldevron, LLC: SWOT Analysis
Figure 12.4: Boehringer Ingelheim: Product Portfolio for the Global Viral Vector and Plasmid Manufacturing Market
Figure 12.5: Boehringer Ingelheim: SWOT Analysis
Figure 12.6: Catalent, Inc: Service / Product Portfolio for Global Viral Vector and Plasmid Manufacturing Market
Figure 12.7: Catalent, Inc: Overall Financials, 2017-2019
Figure 12.8: Catalent, Inc.: Net Revenue (by Business Segment), 2017-2019
Figure 12.9: Catalent, Inc.: Net Revenue (by Region), 2017-2019
Figure 12.10: Catalent, Inc.: R&D Expense, 2017-2019
Figure 12.11: Catalent, Inc.: SWOT Analysis
Figure 12.12: FUJIFILM Holdings Corporation: Service / Product Portfolio for the Global Viral Vector and Plasmid Manufacturing Market
Figure 12.13: FUJIFILM Holdings Corporation: Overall Financials, 2017-2019
Figure 12.14: FUJIFILM Holdings Corporation: Net Revenue (by Business Segment), 2017-2019
Figure 12.15: FUJIFILM Holdings Corporation: Healthcare and Material Solutions Revenue (by Sub-Segment), 2017-2019
Figure 12.16: FUJIFILM Holdings Corporation: R&D Expense, 2017-2019
Figure 12.17: FUJIFILM Holdings Corporation: SWOT Analysis
Figure 12.18: GE Healthcare: Service / Product Portfolio for the Global Viral Vector and Plasmid Manufacturing Market
Figure 12.19: GENERAL ELECTRIC Company: Overall Financials, 2017-2019
Figure 12.20: GENERAL ELECTERIC: Revenue (by Business Model), 2017-2019
Figure 12.21: GENERAL ELECTRIC: Revenue (by Region), 2017-2019
Figure 12.22: GENERAL ELECTRIC: R&D Expenditure, 2017-2019
Figure 12.23: GENERAL ELECTRIC: SWOT Analysis
Figure 12.24: GenScript: Service / Product Portfolio for the Global Viral Vector and Plasmid Manufacturing Market
Figure 12.25: GenScript: Overall Financials, 2016-2018
Figure 12.26: GenScript: R&D Expense, 2016-2018
Figure 12.27: GenScript: SWOT Analysis
Figure 12.28: Lonza: Service / Product Portfolio for Global Viral Vector and Plasmid Manufacturing Market
Figure 12.29: Lonza: Overall Financials, 2017-2019
Figure 12.30: Lonza: Revenue (by Segment), 2017-2019
Figure 12.31: Lonza: Revenue (by Region), 2017-2019
Figure 12.32: Lonza: R&D Expenditure (2017-2019)
Figure 12.33: Lonza: SWOT Analysis
Figure 12.35: Merck KGaA: Overall Financials, 2017-2019
Figure 12.36: Merck KGaA: Revenue (by Product and Services), 2017-2019
Figure 12.37: Merck KGaA: Revenue (by Region), 2017-2019
Figure 12.38: Merck KGaA: R&D Expenditure, 2017-2019
Figure 12.40: MolMed S.p.A.: Service / Product Portfolio for the Global Viral Vector and Plasmid Manufacturing Market
Figure 12.41: MolMed S.p.A.: Overall Financials, 2016-2018
Figure 12.42: MolMed S.p.A.: SWOT Analysis
Figure 12.43: Novasep Holding SAS: Service / Product Portfolio for the Global Viral Vector and Plasmid Manufacturing Market
Figure 12.44: Novasep Holding SAS: SWOT Analysis
Figure 12.45: Oxford Biomedica plc: Service / Product Portfolio for Global Viral Vector and Plasmid Manufacturing Market
Figure 12.46: Oxford Biomedica plc: Overall Financials, 2016-2018
Figure 12.47: Oxford Biomedica plc: Revenue (by Segment), 2016-2018
Figure 12.48: Oxford Biomedica plc: R&D Expenditure (2016-2018)
Figure 12.49: Oxford Biomedica plc: SWOT Analysis
Figure 12.50: Sartorius AG: Service/Product Portfolio for the Global Viral Vector and Plasmid Manufacturing Market
Figure 12.51: Sartorius AG: Overall Financials, 2017-2019
Figure 12.52: Sartorius AG: Revenue (by Business Segment), 2017-2019
Figure 12.53: Sartorius AG: Revenue (by Region), 2017-2019
Figure 12.54: Sartorius AG: R&D Expenditure (2017-2019)
Figure 12.55: Sartorius AG: SWOT Analysis
Figure 12.56: Takara Bio Inc.: Service/Product Portfolio for the Global Viral Vector and Plasmid Manufacturing Market
Figure 12.57: Takara Bio Inc.: Overall Financials, 2017-2019
Figure 12.58: Takara Bio Inc.: Revenue (by Business Segment), 2017-2019
Figure 12.59: Takara Bio Inc.: Revenue (by Region), 2017-2019
Figure 12.60: Takara Bio Inc.: R&D Expenditure (2017-2019)
Figure 12.61: Takara Bio Inc.: SWOT Analysis
Figure 12.62: Thermo Fisher Scientific, Inc.: Service / Product Portfolio for the Global Viral Vector and Plasmid Manufacturing Market
Figure 12.63: Thermo Fisher Scientific, Inc.: Overall Financials, 2017-2019
Figure 12.64: Thermo Fisher Scientific, Inc.: Revenue (by Business Segment), 2017-2019
Figure 12.65: Thermo Fisher Scientific, Inc.: Revenue (by Region), 2017-2019
Figure 12.66: Thermo Fisher Scientific, Inc.: R&D Expenditure (2017-2019)
Figure 12.67: Thermo Fisher Scientific, Inc.: SWOT Analysis
Figure 12.68: WuXi AppTec: Service / Product Portfolio for the Global Viral Vector and Plasmid Manufacturing Market
Figure 12.69: WuXi AppTec: Overall Financials, 2016-2018
Figure 12.70: WuXi AppTec: Net Revenue (by Business Segment), 2016-2018
Figure 12.71: WuXi AppTec: Net Revenue (by Region), 2016-2018
Figure 12.72: WuXi AppTec: R&D Expense, 2016-2018
Figure 12.73: WuXi AppTec: SWOT Analysis
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Base Year |
2019 |
Market Size in 2019 |
$1,158.44 Million |
Forecast Period |
2020-2030 |
Value Projection and Estimation by 2030 |
$ 5,862.22 Million |
CAGR During Forecast Period |
16.28% |
Number of Tables |
14 |
Number of Pages |
275 |
Number of Figures |
157 |
Research Hours |
700 |
|
|
Market Segmentation |
• Vector Type – Plasmid DNA and Viral Vector • Viral Vector Type – Adenovirus, Adeno-Associated Virus, Retrovirus, Lentivirus, Vaccinia Virus, and Other Viral Vectors • Disease Type – Cancer, Genetic Disease, Infectious Disease, Cardiovascular Disease, and Other Diseases • Application – Gene Therapy, Cell Therapy, Vaccinology, and Other Applications |
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Regional Segmentation |
• North America – U.S., Canada • Europe – Germany, U.K., France, Italy, Switzerland, Belgium Spain, and Rest-of-Europe • Asia-Pacific – China, Australia, Japan, India, South Korea, Singapore, and Rest-of-Asia-Pacific • Rest-of-the-World – Latin America and Middle-East and Africa |
||
Growth Drivers |
• Rising Prevalence of Cancer, Genetic Disorders, and Infectious Diseases • Rapid Uptake of Viral and Plasmid Vectors for the Development of Innovative Therapies • Increasing Number of Clinical Studies for the Development of Gene Therapy • Favorable Funding Scenario for Vector-Based Therapies |
||
Market Challenges |
• Unaffordable Cost of Gene Therapies • High Manufacturing Costs of Viral Vectors and Plasmids • Complications Associated with Large-Scale Production of Vectors |
||
Market Opportunities |
• Rising Demand for Synthetic Genes • Emergence of Next-Generation Vectors
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Key Companies Profiled |
FUJIFILM Holdings Corporation, GENERAL ELECTRIC, Lonza, Merck KGaA, MolMed S.p.A., Novasep Holding, Oxford Biomedica plc, Catalent, Inc., Thermo Fisher Scientific, Inc., GenScript, Boehringer Ingelheim, Wuxi AppTec Co., Ltd., Sartorius AG, Takara Bio Inc., and Aldevron, L.L.C. |
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• What is a vector and what is its importance in the medical industry? What are the major characteristics and types of vectors? What are the areas of application of vectors?
• What are the major advancements in viral vector and plasmid manufacturing? What are the key trends of the global viral vector and plasmid manufacturing market? How is the market evolving and what is its future scope?
• What are the major drivers, challenges, and opportunities of the global viral vector and plasmid manufacturing market?
• What are the key developmental strategies implemented by the key players of the global viral vector and plasmid manufacturing market to sustain the competition of the market? What is the percentage share of each of the key players in different key developmental strategies?
• What is the regulatory scenario of the global viral vector and plasmid manufacturing market? What are the initiatives implemented by different governmental bodies and guidelines put forward to regulate the commercialization of viral vector and plasmid manufacturing products?
• What are major milestones in patenting activity in the global viral vector and plasmid manufacturing market?
• What was the market size of the global viral vector and plasmid manufacturing market in 2019 and what is the market size anticipated to be in 2030? What is the expected growth rate of the global viral vector and plasmid manufacturing market during the period between 2020 and 2030?
• What is the global market size for manufacturing plasmids and different types of viral vectors available in the global viral vector and plasmid manufacturing market in 2019? What are the key trends of the market with respect to different vectors and which vector type is expected to dominate the market in 2030?
• What are the different disease areas where plasmids and viral vectors are employed in the global viral vector and plasmid manufacturing market? Which disease type dominated the market in 2019 and is expected to dominate in 2030?
• What are the different applications associated with viral vector and plasmid manufacturing? What was the contribution of each of the application areas in the global viral vector and plasmid manufacturing market in 2019 and what is it expected in 2030?
• Which region is expected to contribute the highest sales in the global viral vector and plasmid manufacturing market during the period between 2019 and 2030? Which region and country carries the potential for the significant expansion of key companies for different viral vector and plasmid manufacturing? What are the leading countries of different regions that contribute significantly toward the growth of the viral vector and plasmid manufacturing market?
• What are the key players of the global viral vector and plasmid manufacturing market and what is their role in the market? What is the market share of the key players in 2019?
The ability of vectors to carry out genetic modification through the introduction of therapeutic DNA/gene into a patient's body or cell has enabled its application in a wide range of modern therapies, including cell and gene therapies. Growing prominence of these therapies in different medical applications have therefore resulted in an increased demand for both viral and non-viral vectors. Vector-based therapies are currently being used for the treatment of a large number of diseases, including cancer, infectious diseases, genetic diseases, and cardiovascular diseases, among others. Viral vectors and plasmid reduce the cost of treatment and help in decreasing repeated administrations of medications. Moreover, vectors are also increasingly being used in the field of vaccinology for the development of vaccines owing to the advantage offered by them in inducing a wide range of immune response types. Several players, including biopharmaceutical companies, research institutes, contract manufacturing organizations, and non-profit organizations, have therefore focussed their interest on the development and production of viral vectors and plasmids.
Our healthcare experts have found viral vector and plasmid manufacturing industry to be one of the most rapidly evolving market, and the global market for viral vector and plasmid manufacturing is predicted to grow at a CAGR of 16.28% over the forecast period of 2020-2030. The market is driven by certain factors, which include success of vector-based cell and gene therapies in treating various therapeutic conditions, increasing number of clinical studies in the field of gene therapy and availability of funding for vector-based gene therapy development, technological advancements in the biomanufacturing sector, and growing investments for expanding vector manufacturing facilities.
The market is favoured by the rising prevalence of genetic disorders, cancer, and infectious diseases that has raised the demand for advanced therapeutics and increasing acceptance for comparatively newer treatment options in developing countries. However, the growth of the market is also affected by several factors. Exorbitant manufacturing cost and highly regulated processes for large-scale vector production are the key challenges cited by industry experts. In addition, lack of required infrastructure and the shortfall of expertise in terms of scale, complexities, and quality assurance for vector production are some of the factors restraining the market growth. However, rise of contract manufacturers has effectively addressed the above-articulated manufacturing challenges by offering a wide range of vector manufacturing services that offer lucrative opportunities for the growth of the market. Further, increasing in research and developmental activities in vector engineering offer strong promise to drive the growth of the viral vector and plasmid manufacturing market in the upcoming years.
Within the research report, the market is segmented on the basis of vector type, application, disease, and region. Each of these segments covers the snapshot of the market over the projected years, the inclination of the market revenue, underlying patterns, and trends by using analytics on the primary and secondary data obtained.
The exponential rise in the application of viral vector and plasmid in various therapies on the global level has created a buzz among companies to invest significantly in viral vector and plasmid manufacturing market. The market is highly competitive, marking the presence of several contract manufacturing organizations and biopharmaceutical companies, who are engaged in in-house vector manufacturing. Among the different players of the market, Lonza and Thermo Fisher Scientific hold majority of the market share. Other companies contributing significantly toward the growth of the global viral vector and plasmid manufacturing market include GE Healthcare, Fujifilm Holding Corporation, Merck KGaA, Oxford Biomedica plc, Sartorius AG, and Catalent, Inc., among others. On the basis of region, North America holds the largest market share, while Asia-Pacific region are anticipated to grow at the fastest CAGR during the forecast period.
List of Tables
Table 1: Leading Segments of the Global Viral Vector and Plasmid Manufacturing Market, 2019 and 2030
Table 4.1: Advantages and Disadvantages of Common Viral Vectors and Plasmids
Table 5.1: Gene Therapy for Different Types of Cancer
Table 5.2: Recent Approvals for Gene Therapy
Table 5.3: Companies Offering Gene Therapies and Their Cost
Table 6.1: Global Regulatory Scenario
Table 6.2: Patents Related to Viral Vectors and Plasmids (January 2017-February 2020)
Table 8.1: Examples of Viral Vectors Used in Gene Therapy
Table 8.2: Plasmids Used in Gene Therapy Trials
Table 9.1: Examples of Ad Vectors for Cancer Gene Therapy
Table 9.2: Features of Vectors Used in Cardiovascular Therapy
Table 10.1: Examples of Clinical Trials Using Viral Vectors
Table 10.2: Advantages and Disadvantages Associated with Major Viral Vectors
Table 11.1: Examples of Key Companies with Headquarters in the U.S.
List of Figures
Figure 1: Global Viral Vector and Plasmid Manufacturing Market (by Region), 2019 and 2030
Figure 2: Key Players of the Global Viral Vector and Plasmid Manufacturing Market
Figure 3: Drivers, Challenges, and Opportunities of the Global Viral Vector and Plasmid Manufacturing Market
Figure 4: Share of Key Developments and Strategies, January 2017-February 2020
Figure 5: Global Viral Vector and Plasmid Manufacturing Market (by Vector Type), 2019 and 2030
Figure 6: Global Viral Vector and Plasmid Manufacturing Market (by Viral Vector), 2019 and 2030
Figure 7: Global Viral Vector and Plasmid Manufacturing Market (by Disease), 2019 and 2030
Figure 8: Global Viral Vector and Plasmid Manufacturing Market (by Application), 2019 and 2030
Figure 2.1: Global Viral Vector and Plasmid Manufacturing Market Segmentation
Figure 3.1: Global Viral Vector and Plasmid Manufacturing Market Research Methodology
Figure 3.2: Primary Research
Figure 3.3: Secondary Research
Figure 3.4: Data Triangulation
Figure 3.5: Bottom-up Approach (Segment-Wise Analysis)
Figure 3.6: Top-Down Approach (Segment-Wise Analysis)
Figure 3.7: Assumptions and Limitations
Figure 4.1: Mechanism of Action of Vectors
Figure 4.2: Evolutionary History of Vectors
Figure 4.3: Typical Production Methods of Viral Vectors and Plasmids
Figure 4.4: Global Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 5.1: Drivers, Challenges, and Opportunities of the Global Viral Vector and Plasmid Manufacturing Market
Figure 5.2: Estimated New Cancer Cases and Deaths (by Sex), U.S., 2020
Figure 6.1: Workflow Associated With Biomanufacturing
Figure 6.2: Global Viral Vector and Plasmid Manufacturing Market: Patent Analysis (by Year of Publication), June 2017-December 2019
Figure 7.1: Competitive Landscape, January 2017- March 2020
Figure 7.2: Share of Key Developments and Strategies, January 2017-February 2020
Figure 7.3: Partnerships and Alliances (by Company), January 2017-February 2020
Figure 7.4: Business Expansions (by Company), January 2017-February 2020
Figure 7.5: New Offerings (by Company), January 2017-February 2020
Figure 7.6: M&A Activities (by Company), January 2017-February 2020
Figure 7.7: Others (by Company), January 2017-February 2020
Figure 7.8: Market Share Analysis of Global Viral Vector and Plasmid Manufacturing Market, 2019
Figure 8.1: Global Viral Vector and Plasmid Manufacturing Market Segmentation (by Vector)
Figure 8.2: Global Viral Vector and Plasmid Manufacturing Market (by Vector Type), 2019 and 2030
Figure 8.3: Global Viral Vector and Plasmid Manufacturing Market for Viral Vectors, 2019-2030
Figure 8.4: Global Viral Vector and Plasmid Manufacturing Market (by Viral Vector), 2019 and 2030
Figure 8.5: Global Viral Vector and Plasmid Manufacturing Market for Adenoviral Vectors, 2019-2030
Figure 8.6: Global Viral Vector and Plasmid Manufacturing Market for Retroviral Vectors, 2019-2030
Figure 8.7: Global Viral Vector and Plasmid Manufacturing Market for Adeno-Associated Viral Vectors, 2019-2030
Figure 8.8: Global Viral Vector and Plasmid Manufacturing Market for Lentiviral Vectors, 2019-2030
Figure 8.9: Global Viral Vector and Plasmid Manufacturing Market for Vaccinia Viral Vectors, 2019-2030
Figure 8.10: Global Viral Vector and Plasmid Manufacturing Market for Other Viral Vectors, 2019-2030
Figure 8.11: Global Viral Vector and Plasmid Manufacturing Market for Viral Vectors, 2019-2030
Figure 9.1: Global Viral Vector and Plasmid Manufacturing Market Segmentation (by Disease)
Figure 9.2: Global Viral Vector and Plasmid Manufacturing Market (by Disease), 2019 and 2030
Figure 9.3: Global Viral Vector and Plasmid Manufacturing Market for Cancer, 2019-2030
Figure 9.4: List of Monogenic Disorders for which Human Gene Transfer Trials Have Been Approved
Figure 9.5: Global Viral Vector and Plasmid Manufacturing Market for Genetic Diseases, 2019-2030
Figure 9.6: Global Viral Vector and Plasmid Manufacturing Market for Infectious Diseases, 2019-2030
Figure 9.7: Global Viral Vector and Plasmid Manufacturing Market for Infectious Diseases, 2019-2030
Figure 9.8: Global Viral Vector and Plasmid Manufacturing Market for Other Diseases, 2019-2030
Figure 10.1: Global Viral Vector and Plasmid Manufacturing Market Segmentation (by Application)
Figure 10.2: Global Viral Vector and Plasmid Manufacturing Market (by Application), 2019 and 2030
Figure 10.3: Global Viral Vector and Plasmid Manufacturing Market for Gene Therapy, 2019-2030
Figure 10.4: Global Viral Vector and Plasmid Manufacturing Market for Vaccinology, 2019-2030
Figure 10.5: Global Viral Vector and Plasmid Manufacturing Market for Cell Therapy, 2019-2030
Figure 10.6: Global Viral Vector and Plasmid Manufacturing Market for Cell Therapy, 2019-2030
Figure 11.1: Global Viral Vector and Plasmid Manufacturing Market (by Region), 2019 and 2030
Figure 11.2: North America: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.3: North America: Market Dynamics
Figure 11.4: North America: Viral Vector and Plasmid Manufacturing Market (by Country), 2019 and 2030
Figure 11.5: U.S.: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.6: Canada: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.7: Europe: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.8: Europe: Market Dynamics
Figure 11.9: Europe: Viral Vector and Plasmid Manufacturing Market (by Country), 2019 and 2030
Figure 11.10: Germany: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.11: U.K.: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.12: France: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.13: Italy: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.14: Switzerland: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.15: Belgium: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.16: Spain: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.17: Rest-of-Europe: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.18: Asia-Pacific: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.19: Asia-Pacific: Market Dynamics
Figure 11.20: Asia-Pacific: Viral Vector and Plasmid Manufacturing Market (by Country), 2019 and 2030
Figure 11.21: China: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.22: Australia: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.23: Japan: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.24: India: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.25: South Korea: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.26: Singapore: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.27: Rest-of-Asia-Pacific: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.28: Rest-of-the-World: Viral Vector and Plasmid Manufacturing Market, 2019-2030
Figure 11.29: Rest-of-the-World: Viral Vector and Plasmid Manufacturing Market (Latin America and Middle-East and Africa), 2019-2030
Figure 12.1: Shares of Key Company Profiles
Figure 12.2: Aldevron, LLC: Service / Product Portfolio for Global Viral Vector and Plasmid Manufacturing Market
Figure 12.3: Aldevron, LLC: SWOT Analysis
Figure 12.4: Boehringer Ingelheim: Product Portfolio for the Global Viral Vector and Plasmid Manufacturing Market
Figure 12.5: Boehringer Ingelheim: SWOT Analysis
Figure 12.6: Catalent, Inc: Service / Product Portfolio for Global Viral Vector and Plasmid Manufacturing Market
Figure 12.7: Catalent, Inc: Overall Financials, 2017-2019
Figure 12.8: Catalent, Inc.: Net Revenue (by Business Segment), 2017-2019
Figure 12.9: Catalent, Inc.: Net Revenue (by Region), 2017-2019
Figure 12.10: Catalent, Inc.: R&D Expense, 2017-2019
Figure 12.11: Catalent, Inc.: SWOT Analysis
Figure 12.12: FUJIFILM Holdings Corporation: Service / Product Portfolio for the Global Viral Vector and Plasmid Manufacturing Market
Figure 12.13: FUJIFILM Holdings Corporation: Overall Financials, 2017-2019
Figure 12.14: FUJIFILM Holdings Corporation: Net Revenue (by Business Segment), 2017-2019
Figure 12.15: FUJIFILM Holdings Corporation: Healthcare and Material Solutions Revenue (by Sub-Segment), 2017-2019
Figure 12.16: FUJIFILM Holdings Corporation: R&D Expense, 2017-2019
Figure 12.17: FUJIFILM Holdings Corporation: SWOT Analysis
Figure 12.18: GE Healthcare: Service / Product Portfolio for the Global Viral Vector and Plasmid Manufacturing Market
Figure 12.19: GENERAL ELECTRIC Company: Overall Financials, 2017-2019
Figure 12.20: GENERAL ELECTERIC: Revenue (by Business Model), 2017-2019
Figure 12.21: GENERAL ELECTRIC: Revenue (by Region), 2017-2019
Figure 12.22: GENERAL ELECTRIC: R&D Expenditure, 2017-2019
Figure 12.23: GENERAL ELECTRIC: SWOT Analysis
Figure 12.24: GenScript: Service / Product Portfolio for the Global Viral Vector and Plasmid Manufacturing Market
Figure 12.25: GenScript: Overall Financials, 2016-2018
Figure 12.26: GenScript: R&D Expense, 2016-2018
Figure 12.27: GenScript: SWOT Analysis
Figure 12.28: Lonza: Service / Product Portfolio for Global Viral Vector and Plasmid Manufacturing Market
Figure 12.29: Lonza: Overall Financials, 2017-2019
Figure 12.30: Lonza: Revenue (by Segment), 2017-2019
Figure 12.31: Lonza: Revenue (by Region), 2017-2019
Figure 12.32: Lonza: R&D Expenditure (2017-2019)
Figure 12.33: Lonza: SWOT Analysis
Figure 12.35: Merck KGaA: Overall Financials, 2017-2019
Figure 12.36: Merck KGaA: Revenue (by Product and Services), 2017-2019
Figure 12.37: Merck KGaA: Revenue (by Region), 2017-2019
Figure 12.38: Merck KGaA: R&D Expenditure, 2017-2019
Figure 12.40: MolMed S.p.A.: Service / Product Portfolio for the Global Viral Vector and Plasmid Manufacturing Market
Figure 12.41: MolMed S.p.A.: Overall Financials, 2016-2018
Figure 12.42: MolMed S.p.A.: SWOT Analysis
Figure 12.43: Novasep Holding SAS: Service / Product Portfolio for the Global Viral Vector and Plasmid Manufacturing Market
Figure 12.44: Novasep Holding SAS: SWOT Analysis
Figure 12.45: Oxford Biomedica plc: Service / Product Portfolio for Global Viral Vector and Plasmid Manufacturing Market
Figure 12.46: Oxford Biomedica plc: Overall Financials, 2016-2018
Figure 12.47: Oxford Biomedica plc: Revenue (by Segment), 2016-2018
Figure 12.48: Oxford Biomedica plc: R&D Expenditure (2016-2018)
Figure 12.49: Oxford Biomedica plc: SWOT Analysis
Figure 12.50: Sartorius AG: Service/Product Portfolio for the Global Viral Vector and Plasmid Manufacturing Market
Figure 12.51: Sartorius AG: Overall Financials, 2017-2019
Figure 12.52: Sartorius AG: Revenue (by Business Segment), 2017-2019
Figure 12.53: Sartorius AG: Revenue (by Region), 2017-2019
Figure 12.54: Sartorius AG: R&D Expenditure (2017-2019)
Figure 12.55: Sartorius AG: SWOT Analysis
Figure 12.56: Takara Bio Inc.: Service/Product Portfolio for the Global Viral Vector and Plasmid Manufacturing Market
Figure 12.57: Takara Bio Inc.: Overall Financials, 2017-2019
Figure 12.58: Takara Bio Inc.: Revenue (by Business Segment), 2017-2019
Figure 12.59: Takara Bio Inc.: Revenue (by Region), 2017-2019
Figure 12.60: Takara Bio Inc.: R&D Expenditure (2017-2019)
Figure 12.61: Takara Bio Inc.: SWOT Analysis
Figure 12.62: Thermo Fisher Scientific, Inc.: Service / Product Portfolio for the Global Viral Vector and Plasmid Manufacturing Market
Figure 12.63: Thermo Fisher Scientific, Inc.: Overall Financials, 2017-2019
Figure 12.64: Thermo Fisher Scientific, Inc.: Revenue (by Business Segment), 2017-2019
Figure 12.65: Thermo Fisher Scientific, Inc.: Revenue (by Region), 2017-2019
Figure 12.66: Thermo Fisher Scientific, Inc.: R&D Expenditure (2017-2019)
Figure 12.67: Thermo Fisher Scientific, Inc.: SWOT Analysis
Figure 12.68: WuXi AppTec: Service / Product Portfolio for the Global Viral Vector and Plasmid Manufacturing Market
Figure 12.69: WuXi AppTec: Overall Financials, 2016-2018
Figure 12.70: WuXi AppTec: Net Revenue (by Business Segment), 2016-2018
Figure 12.71: WuXi AppTec: Net Revenue (by Region), 2016-2018
Figure 12.72: WuXi AppTec: R&D Expense, 2016-2018
Figure 12.73: WuXi AppTec: SWOT Analysis
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